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Bisphosphonates were first developed in the nineteenth century. They were first investigated for use in disorders of bone metabolism in the 1960s. They are now used clinically for the treatment of osteoporosis, Paget's disease, bone metastasis, multiple myeloma, and other conditions that feature bone fragility.
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People about to have surgery must tell their health care providers about all supplements they take.
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The ratio of hydrogen atoms to oxygen in water (H2O) is 2:1.
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As of mid-2016, 18.2 million people were receiving advanced retroviral therapy (ART) worldwide. This represents between 43–50% of the 34–39.8 million people living with HIV.
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In 1864, the first barbiturate (barbituric acid) was synthesized.