Answer to Question 1
B
The kidneys are the primary site of excretion. Adequate fluid intake facilitates renal excretion. If the patient has decreased renal function, the nurse should closely monitor for medication toxicity.
Answer to Question 2
C
Drug metabolism takes place mainly in the liver, but medications can also be detoxified in the kidneys, blood plasma, intestinal mucosa, and lungs. If liver function is impaired due to liver disease, medications will be eliminated more slowly, and toxic levels may accumulate.