The nurse is administering a medication to a client at identified ...

[frankwu]

The nurse is administering a medication to a client at identified times in order to maintain a specific amount of the medication in the client's bloodstream at all times. The nurse is ensuring that which action is being maintained for this client?
 
  1. Peak plasma level.
  2. Drug half-life.
  3. Onset of action.
  4. Plateau.

Question 2

A client is diagnosed with liver disease. The nurse realizes that which element of pharmacokinetics will be affected in this client?
 
  1. Absorption.
  2. Distribution.
  3. Biotransformation.
  4. Excretion.

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Answer to Question 1

Correct Answer: 4
Rationale 1: Peak plasma level is the highest plasma level achieved by a single dose when the elimination rate of the drug equals the absorption rate.
Rationale 2: Drug half-life is the time required for the elimination process to reduce the concentration of the drug to one-half of what it was at initial administration.
Rationale 3: Onset of action is the time after administration when the body initially responds to the drug.

Answer to Question 2

Correct Answer: 3
Rationale 1: Absorption is the process by which a drug passes into the bloodstream.
Rationale 2: Distribution is the transportation of a drug from its site of absorption to its site of action.
Rationale 3: Biotransformation, also called detoxification or metabolism, is a process by which a drug is converted to a less active form. Most biotransformation takes place in the liver. Biotransformation can be altered if a person has an unhealthy liver.
Rationale 4: Excretion is the process by which metabolites and drugs are eliminated from the body. Most drug metabolites are eliminated by the kidneys via the urine.

[frankwu]

Excellent

[Zebsrer]

TYSM