Why must sulfonamide drugs be avoided during the last trimester of pregnancy and lactation?
a. The drug crosses the placenta and causes brain hemorrhage in the fetus.
b. The fetal and newborn liver cannot metabolize the drug and jaundice results.
c. The fetus and newborn are more likely to have allergic reactions to sulfonamides.
d. The drug interferes with tooth enamel development causing permanently stained teeth.
Question 2
A patient is taking trimethoprim (Primsol) 200 mg orally once a day. For which adverse effect will you monitor?
a. GI bleeding
b. Kidney failure
c. Anaphylaxis
d. Angioedema