This topic contains a solution. Click here to go to the answer

Author Question: Which of the following statements most accurately describes the action of colestipol (Colestid) in ... (Read 110 times)

ssal

  • Hero Member
  • *****
  • Posts: 572
Which of the following statements most accurately describes the action of colestipol (Colestid) in the reduction of serum cholesterol levels?
 
  a. It prevents synthesis of cholesterol by the liver.
  b. It inhibits the secretion of cholesterol by the liver into bile salts.
  c. It prevents the uptake of excess cholesterol from the blood stream by the liver.
  d. It binds to bile salts in the gastrointestinal (GI) tract, preventing their reabsorp-tion.

Question 2

Which of the following variables must be considered when the decision to start antihypertensive drug therapy is being initiated? Select all that apply.
 
  a. Stage and degree of blood pressure elevation
  b. Adherence to therapy with once-daily dosing
  c. Presence of clinical cardiovascular or other risk factors
  d. Presence of end-organ damage
  e. Safety profile of the specific drug or drugs
  f. Reduced risk of sudden death, heart attack, and stroke caused by abrupt increases in blood pressure after arising



Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

shewald78

  • Sr. Member
  • ****
  • Posts: 340
Answer to Question 1

ANS: D
Bile acid resins such as colestipol are anion-exchange resins that reduce low-density lipoprotein (LDL) levels by binding bile salts in exchange for chloride ions. These drugs form an insoluble complex with bile acids in the intestine. The bile acid-drug complex prevents the reabsorption of the bile acids, thus increasing their elimination. In an attempt to compensate for the loss of bile salts, the liver raises the rate of bile acid synthesis.

Answer to Question 2

ANS: A, C, D, E
The decision to start antihypertensive drug therapy requires careful consideration of several fac-tors including the following:
 Stage and degree of blood pressure elevation
 Presence of clinical cardiovascular or other risk factors
 Presence of end-organ damage
 Safety profile of the specific drug or drugs
 Efficacy and convenience of specific drug or drugs
 Potential for drug interactions
Treatment costs, including laboratory testing, and follow-up visits to health care provider.




ssal

  • Member
  • Posts: 572
Reply 2 on: Jul 23, 2018
Excellent


aruss1303

  • Member
  • Posts: 314
Reply 3 on: Yesterday
Gracias!

 

Did you know?

Giardia is one of the most common intestinal parasites worldwide, and infects up to 20% of the world population, mostly in poorer countries with inadequate sanitation. Infections are most common in children, though chronic Giardia is more common in adults.

Did you know?

Human kidneys will clean about 1 million gallons of blood in an average lifetime.

Did you know?

In the United States, there is a birth every 8 seconds, according to the U.S. Census Bureau's Population Clock.

Did you know?

Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.

Did you know?

Although not all of the following muscle groups are commonly used, intramuscular injections may be given into the abdominals, biceps, calves, deltoids, gluteals, laterals, pectorals, quadriceps, trapezoids, and triceps.

For a complete list of videos, visit our video library