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In ancient Rome, many of the richer people in the population had lead-induced gout. The reason for this is unclear. Lead poisoning has also been linked to madness.
People about to have surgery must tell their health care providers about all supplements they take.
According to the FDA, adverse drug events harmed or killed approximately 1,200,000 people in the United States in the year 2015.
More than 4.4billion prescriptions were dispensed within the United States in 2016.
It is believed that the Incas used anesthesia. Evidence supports the theory that shamans chewed cocoa leaves and drilled holes into the heads of patients (letting evil spirits escape), spitting into the wounds they made. The mixture of cocaine, saliva, and resin numbed the site enough to allow hours of drilling.