To prevent systemic absorption of timolol (Timoptic), what ...

[tiffannnnyyyyyy]

To prevent systemic absorption of timolol (Timoptic), what administration instructions are appropriate for the nurse to include in the teaching?
 
  1. Apply pressure over the lacrimal sac for 1 minute.
  2. Wait 5 minutes before administering other ophthalmic solutions.
  3. Administer the eyedrop in the conjunctival sac.
  4. Remove contact lenses prior to administering eyedrops.

Question 2

What is the most appropriate explanation as to why dipivefrin hydrochloride (Propine) effectively decreases intraocular pressure?
 
  1. The exact mechanism is not fully understood.
  2. It decreases the formation of aqueous humor.
  3. It reduces plasma volume very quickly.
  4. It converts to epinephrine and increases outflow of aqueous humor.

[Dominic]

Answer to Question 1

1

Rationale 1: Applying pressure over the lacrimal sac for 1 minute will decrease systemic absorption.
Rationale 2: This will not decrease systemic absorption.
Rationale 3: This will not decrease systemic absorption.
Rationale 4: This will not decrease systemic absorption.

Global Rationale: Applying pressure over the lacrimal sac for 1 minute will decrease systemic absorption. Waiting 5 minutes between medication administration will not decrease systemic absorption. Administering the medication in the conjunctival sac will not decrease systemic absorption. Removing contact lenses prior to administering the medication will not decrease systemic absorption.

Answer to Question 2

4

Rationale 1: Beta-blocking agents decrease the formation of aqueous humor, but the exact mechanism is not fully understood.
Rationale 2: Beta-blocking agents decrease the formation of aqueous humor, but the exact mechanism is not fully understood.
Rationale 3:Osmotic diuretics reduce plasma volume very quickly.
Rationale 4: Sympathomimetic drugs such as dipivefrin (Propine) convert to epinephrine and produce mydriasis, which is the increased outflow of aqueous humor and the subsequent fall of IOP.

Global Rationale: Sympathomimetic drugs such as dipivefrin (Propine) convert to epinephrine and produce mydriasis, which is the increased outflow of aqueous humor and the subsequent fall of IOP.

[tiffannnnyyyyyy]

Thank you!

[Dominic]

Always glad to help...