Answer to Question 1
1, 3, 4, 5
Rationale 1: Water is the most important molecule reabsorbed in the tubule.
Rationale 2: Hydrogen ions are not reabsorbed.
Rationale 3: Glucose is reabsorbed in the tubule.
Rationale 4: Sodium is reabsorbed in the tubule.
Rationale 5: Amino acids are reabsorbed.
Global Rationale: Water, glucose, amino acids, and essential ions such as sodium, chloride, calcium, and bicarbonate are reabsorbed in the tubule.
Answer to Question 2
1
Rationale 1:Reabsorption and secretion are critical to the pharmacokinetics of many drugs in the kidney.
Rationale 2: Digestion is completed by the GI tract and excretion is pertinent to the kidneys.
Rationale 3: Diuretics promote diuresis and elimination but these are not the pharmacokinetics of the kidney.
Rationale 4: Ingestion and recirculation are not relevant to the pharmacokinetics or movement of fluid by the kidney.
Global Rationale: Reabsorption and secretion are critical to the pharmacokinetics of many drugs in the kidney. Some drugs are reabsorbed, whereas others are secreted into the filtrate.
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