Answer to Question 1
2,3
Rationale 1: Alcohol may potentiate the effects of nifedipine (Adalat CC), but this combination does not cause gastric irritation.
Rationale 2: Concurrent use with melatonin may increase blood pressure and heart rate.
Rationale 3: Grapefruit juice may enhance absorption of nifedipine (Adalat CC).
Rationale 4: Caffeine is not contraindicated when taking nifedipine (Adalat CC).
Rationale 5: Vitamin C supplements are not contraindicated when taking nifedipine (Adalat CC).
Global Rationale: Concurrent use with melatonin may increase blood pressure and heart rate. Grapefruit juice may enhance absorption of nifedipine (Adalat CC). Alcohol may potentiate the effects of nifedipine (Adalat CC), but this combination does not cause gastric irritation. Caffeine and vitamin C supplements are not contraindicated when taking nifedipine (Adalat CC).
Answer to Question 2
3
Rationale 1: NREM stage 3 sleep is the deepest stage of sleep. Patients who are deprived of it experience depression and a feeling of apathy and fatigue.
Rationale 2: Dreaming occurs in REM sleep, not NREM sleep.
Rationale 3: NREM stage 3 is not the lightest stage of sleep.
Rationale 4: REM sleep is often called paradoxical sleep.
Global Rationale: NREM stage 3 sleep is the deepest stage of sleep. Patients who are deprived of it experience depression and feelings of apathy and fatigue. Dreaming occurs in REM sleep, not NREM sleep. NREM stage 3 is not the lightest stage of sleep. REM sleep is often called paradoxical sleep.