Answer to Question 1
4
Rationale 1: Feverfew does not have potential for decreasing the effects of anticonvulsants.
Rationale 2: Goldenseal does not have potential for decreasing the effects of anticonvulsants.
Rationale 3: Ginger does not have potential for decreasing the effects of anticonvulsants.
Rationale 4: Of the listed herbs, ginkgo has the greatest potential for decreasing the effects of anticonvulsants.
Global Rationale: Of the listed herbs, ginkgo has the greatest potential for decreasing the effects of anticonvulsants.
Answer to Question 2
3,4,5
Rationale 1: The best drugs to raise high density lipoprotein (HDL) levels are statins, not fibric acid drugs.
Rationale 2: Niacin, not statins, will cause flushing, which is worse with warm fluids.
Rationale 3: Bile resins are effective, but numerous side effects limit their usefulness.
Rationale 4: Statin drugs inhibit HMG-CoA reductase which is necessary for the biosynthesis of cholesterol and are the drugs of first choice in reducing serum lipid levels.
Rationale 5: Fibric acid agents are effective but will not reduce low density lipoprotein (LDL) levels.
Global Rationale: Fibric acid agents are effective but will not reduce low density lipoprotein (LDL) levels. Statin drugs inhibit HMG-CoA reductase, which is necessary for the biosynthesis of cholesterol and are the drugs of first choice in reducing serum lipid levels. Bile resins are effective, but numerous side effects limit their usefulness. Niacin, not statins, will cause flushing, which is worse with warm fluids. The best drugs to raise high density lipoprotein (HDL) levels are statins, not fibric acid drugs.