In contrast to the barbiturates, the benzodiazepines:
1. cannot cross the blood-brain barrier.
2. have a built-in limit to the depth of CNS depression that they can produce.
3. are not lipid soluble.
4. have more difficulty affecting the CNS.
Question 2
Which drug has replaced lithium as the treatment of choice for bipolar disorder?
1. Clonidine
2. Valproic acid
3. Olanzapine
4. Risperidone