A premenopausal woman has ER-positive breast cancer, and her prescriber has ordered tamoxifen (Nolvadex). She asks the nurse if anastrozole (Arimedex) would work better for her. What will the nurse tell her?
a. Anastrozole is more likely to cause hot flushes than tamoxifen.
b. Anastrozole is more likely to promote endometrial carcinoma.
c. Cancer recurrence is higher with anastrozole.
d. Until she is postmenopausal, anastrozole will not be effective.
Question 2
A 45-year-old patient with a family history of breast cancer is considering using tamoxifen (Nolvadex) for cancer prevention.
The nurse performs a health history and learns that the woman had a child when she was 35 years old, that she has not had a hysterectomy, and that she experienced DVT when she was pregnant. What will the nurse tell the patient?
a. Because of her family risk and late childbearing, this drug is a good choice for her.
b. Her history of DVT outweighs any possible benefits she may have with this drug.
c. Since she has not had a hysterectomy, the risk of endometrial cancer is too great.
d. When she turns 50 years old, this drug will carry fewer risks for her.
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