A client is prescribed an H2-receptor antagonist. The nurse ...

[craiczarry]

A client is prescribed an H2-receptor antagonist. The nurse teaches this client that the purpose of the drug is to:
 
  1. reduce gastric acid secretion in the stomach.
  2. prevent the vasodilating effects of histamine.
  3. alleviate nasal allergy symptoms.
  4. prevent the release of histamine from MAST cells.

Question 2

A client diagnosed with Barrett esophagus might require the most efficient pharmacologic therapy of GERD. This would include the use of which class of drug?
 
  1. Proton pump inhibitor
  2. Antacid
  3. Magnesium citrate
  4. H2-receptor antagonist

[yahahah24021]

Answer to Question 1

Correct Answer: 1
Rationale 1: The H2 receptors, located on the parietal cells in the stomach, promote acid secretion when activated.
Rationale 2: Vasodilation is a symptom of inflammation and allergy associated with H1 receptors.
Rationale 3: Nasal allergy symptoms are caused, in part, by H1 receptors.
Rationale 4: H2 receptor antagonists do not stabilize MAST cells.
Global Rationale: The H2-receptor antagonists suppress gastric acid secretion and are widely prescribed for treating peptic ulcer disease and gastroesophageal reflux disease. They do not prevent the action of histamines, alleviate nasal symptoms, or stabilize MAST cells.

Answer to Question 2

Correct Answer: 1
Rationale 1: The proton pump inhibitors reduce acid secretion to a greater extent than do the H2-receptor antagonists and have a longer duration of action.
Rationale 2: Antacids are not as effective in treating GERD as are proton pump inhibitors.
Rationale 3: Magnesium citrate generally is used as a cathartic and is not indicated for use in the treatment of GERD.
Rationale 4: H2-receptor antagonists are not as effective in treating GERD as are proton pump inhibitors.
Global Rationale: The proton pump inhibitors reduce acid secretion to a greater extent than do the H2-receptor antagonists and have a longer duration of action. Antacids are not as effective in treating GERD as are proton pump inhibitors. Magnesium citrate generally is used as a cathartic and is not indicated for use in the treatment of GERD.

[craiczarry]

Thank you!

[yahahah24021]

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