The nurse is providing chemoprophylaxis drug therapy for a client ...

[rachel9]

The nurse is providing chemoprophylaxis drug therapy for a client who will be traveling to a country with a high incidence of malaria. Which drugs are appropriate for chemoprophylaxis?
 
  Standard Text: Select all that apply.
  1. Chloroquine
  2. Atovaquone-proguanil
  3. Primaquine
  4. Artemether-lumefantrine
  5. Quinine sulfate

Question 2

What drug would the nurse expect to be the first choice of drugs ordered during the chemoprophylaxis stage in the treatment of malaria?
 
  1. Doxycycline
  2. Primaquine
  3. Mefloquine
  4. Chloroquine

[Bsand8]

Answer to Question 1

Correct Answer: 1,2,3
Rationale 1: Chloroquine is a medication that can be used for chemoprophylaxis of malaria.
Rationale 2: Atovaquone-proguanil is a medication that can be used for chemoprophylaxis of malaria.
Rationale 3: Primaquine is a medication that can be used for chemoprophylaxis of malaria.
Rationale 4: Artemether-lumefantrine is a medication used to treat an acute malarial attack and is not used for chemoprophylaxis.
Rationale 5: Quinine sulfate is a medication used to treat an acute malarial attack and is not used for chemoprophylaxis.
Global Rationale: Chloroquine (Aralen) is the traditional drug of choice, unless travel is to a region known to have a high incidence of chloroquine-resistant strains of Plasmodium. Several options are available for patients unable to take chloroquine or for those who are traveling to areas where chloroquine-resistant species are prevalent. These include the combination drugs atovaquone-proguanil (Malarone), doxycycline, mefloquine, or primaquine. Artemether-lumefantrine is a medication used to treat an acute malarial attack and is not used for chemoprophylaxis. Quinine sulfate is a medication used to treat an acute malarial attack and is not used for chemoprophylaxis.

Answer to Question 2

Correct Answer: 4
Rationale 1: Doxycycline is a second-line agent.
Rationale 2: Primaquine is a second-line agent.
Rationale 3: Mefloquine is a second-line agent.
Rationale 4: The first-line agent for prophylaxis for malaria is chloroquine.
Global Rationale: The Centers for Disease Control and Prevention (CDC) recommends that travelers to infested areas receive prophylactic antimalarial drugs prior to travel, during their visit, and for at least 1 week after leaving. Chloroquine (Aralen) is the traditional drug of choice, unless travel is to a region known to have a high incidence of chloroquine-resistant strains of Plasmodium. Chloroquine therapy begins 1 to 2 weeks before travel, and continues once a week during travel and for 4 weeks after returning. Atovaquone-proguanil (Malarone), doxycycline, mefloquine, or primaquine are options available to patients unable to take chloroquine or to those traveling to areas where chloroquine-resistant species are prevalent.