Author Question: The nurse is administering a drug that antagonizes H-1 histamine receptors. Which is the most likely ... (Read 145 times)

kshipps · **on:** Jul 23, 2018

The nurse is administering a drug that antagonizes H-1 histamine receptors. Which is the most likely expected outcome of this therapy?

1. The client will report that headache is improved.
2. The client will cough less.
3. The client will report less sneezing and tearing.
4. The client will report less wheezing and more energy.

Question 2

The nurse is administering an antihistamine to a client with nasal allergies. The nurse is aware that antihistamines have which distinct limitation?

1. They have potent cholinergic side effects.
2. They block both H-1 and H-2 receptors.
3. They are most effective when taken prophylactically.
4. They are useful only during acute attacks.

parker125 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 3
Rationale 1: Antihistamines are not very effective at relieving headaches.
Rationale 2: Antihistamines do not ease coughing.
Rationale 3: Antihistamines are histamine blockers (H-1 blockers). Histamines are responsible for sneezing, itching, and watery eyes.
Rationale 4: Antihistamines do not relieve wheezing.
Global Rationale: H1-receptor antagonists, also called antihistamines, are drugs that selectively block histamine from reaching its H1 receptors, thus alleviating allergic symptoms. Antihistamines are not very effective at relieving headaches and do not relieve coughing or wheezing.

Answer to Question 2

Correct Answer: 3
Rationale 1: Antihistamines block cholinergic receptors; they have anticholinergic effects and adverse effects.
Rationale 2: Antihistamines block just H-1 receptors.
Rationale 3: Antihistamines are most effective when taken prophylactically for the symptoms of nasal allergies.
Rationale 4: Antihistamines have only limited usefulness during acute attacks.
Global Rationale: Antihistamines are most effective when taken prophylactically to prevent allergic symptoms. Their effectiveness in reversing allergic symptoms that have already manifested is limited. This is because antihistamines block the effect of histamine at its receptor sites. They do not prevent the release of histamine from mast cells. Their effectiveness may diminish with long-term use. Antihistamines block cholinergic receptors; they have anticholinergic effects and adverse effects.