Author Question: Aldosterone antagonist drugs work to lower blood pressure by which mechanism of action? 1. ... (Read 18 times)

Destiiny22 · **on:** Jul 23, 2018

Aldosterone antagonist drugs work to lower blood pressure by which mechanism of action?

1. Blocking the formation of renin in the RAAS pathway
2. Blocking receptors for aldosterone in the kidneys
3. Blocking receptors for aldosterone in the adrenal glands
4. Blocking the AT1 receptors in the RAAS pathway

Question 2

Angiotensin receptor blockers (ARBs) work in the body to lower blood pressure by which mechanism of action?

1. Inhibiting the stimulation of aldosterone secretion
2. Blocking the conversion of angiotensin I to angiotensin II
3. Blocking AT1 receptors, which prevent angiotensin from raising blood pressure
4. Blocking the formation of renin in the RAAS system

Bsand8 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 2
Rationale 1: Aldosterone antagonists do not block the formation of renin.
Rationale 2: Aldosterone antagonists block aldosterone receptors in the kidneys, which lowers blood pressure.
Rationale 3: Aldosterone antagonists do not block the aldosterone receptors in the adrenal gland but in the kidney.
Rationale 4: Aldosterone antagonists do not block AT1 receptors.
Global Rationale: Aldosterone antagonists block aldosterone receptors in the kidneys, which lowers blood pressure. Aldosterone antagonists do not block the formation of renin; does not block the aldosterone receptors in the adrenal gland; do not block AT1 receptors.

Answer to Question 2

Correct Answer: 3
Rationale 1: ARBs do not block the stimulation of aldosterone secretion. Aldosterone antagonist drugs work in this way.
Rationale 2: ARBs do not prevent the conversion of angiotensin I to angiotensin II. ACE inhibitor drugs work at this stage of the pathway.
Rationale 3: By blocking the AT1 receptors, the ARBs prevent angiotensin from raising blood pressure.
Rationale 4: ARBs do not block the formation of renin in the RAAS system.
Global Rationale: By blocking the AT1 receptors, the ARBs prevent angiotensin from raising blood pressure. ARBs do not block the stimulation of aldosterone secretion. Aldosterone antagonist drugs work in this way. ARBs do not prevent the conversion of angiotensin I to angiotensin II. ACE inhibitor drugs work at this stage of the pathway. ARBs do not block the formation of renin in the RAAS system.