Author Question: A client who was stung by a bee is treated with an EpiPen auto-injection. Which assessment finding ... (Read 9 times)

jayhills49 · **on:** Jul 23, 2018

A client who was stung by a bee is treated with an EpiPen auto-injection. Which assessment finding indicates that the drug is working?

1. Increased blood pressure
2. Constriction of the pupils
3. Increased urinary output
4. Spasm of the bronchus

Question 2

A client with Parkinson disease who is receiving entacapone (Comtan) is to be given epinephrine for cardiopulmonary resuscitation.

The nurse should be aware that entacapone (Comtan) causes an increased effect of epinephrine on the heart due to which action?
1. Stimulation of the enzyme COMT in the synaptic cleft
2. Inhibition of the enzyme COMT in the synaptic cleft
3. Increased reuptake of the enzyme COMT from the synaptic cleft
4. Excessive secretion of the enzyme COMT from the synaptic vesicles

Jossy · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

Correct Answer: 1
Rationale 1: Immediately after injection, blood pressure increases due to stimulation of alpha-1 receptors.
Rationale 2: Epinephrine causes pupillary dilation, not constriction.
Rationale 3: Epinephrine causes decreased urinary output.
Rationale 4: Epinephrine causes bronchodilation due to activation of beta-2 receptors in the bronchi, so the client can breathe freely.
Global Rationale: Immediately after injection, blood pressure increases due to stimulation of alpha-1 receptors. Epinephrine causes pupillary dilation, not constriction. Epinephrine causes decreased urinary output. Epinephrine causes bronchodilation due to activation of beta-2 receptors in the bronchi, so the client can breathe freely.

Answer to Question 2

Correct Answer: 2
Rationale 1: Entacapone (Comtan) causes inhibition, not stimulation, of COMT in the synaptic cleft.
Rationale 2: Entacapone (Comtan) causes inhibition of COMT in the synaptic cleft. This causes an increased effect of epinephrine on the heart and blood pressure.
Rationale 3: Entacapone (Comtan) does not cause reuptake of COMT in the synaptic cleft.
Rationale 4: Entacapone (Comtan) does not cause excessive secretion of COMT.
Global Rationale: Entacapone (Comtan) causes inhibition of COMT in the synaptic cleft. This causes an increased effect of epinephrine on the heart and blood pressure. Entacapone (Comtan) does not cause reuptake of COMT in the synaptic cleft, nor does it cause excessive secretion of COMT.