Answer to Question 1
Correct Answer: 1,2,3
Rationale 1: Starting the older adult on the lowest effective dose and titrating upward will decrease the risk for toxicity.
Rationale 2: Drug accumulation in older adults often occurs 3 to 5 days after the new drug has been initiated.
Rationale 3: Consider any change in physical or emotional behavior as a possible sign of toxicity.
Rationale 4: Dehydration causes drug toxicity.
Rationale 5: Low-protein diets can cause drug toxicity.
Global Rationale: Starting the older adult on the lowest effective dose and titrating upward will decrease the risk for toxicity. Drug accumulation in older adults often occurs 3 to 5 days after the new drug has been initiated. Consider any change in physical or emotional behavior as a possible sign of toxicity. Dehydration causes drug toxicity. Low-protein diets can cause drug toxicity.
Answer to Question 2
Correct Answer: 1,2,3
Rationale 1: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the bloodbrain barrier in higher concentrations, resulting in adverse effects.
Rationale 2: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the bloodbrain barrier in higher concentrations, resulting in adverse effects.
Rationale 3: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the bloodbrain barrier in higher concentrations, resulting in adverse effects.
Rationale 4: Antibiotics for pneumonia do not cross the bloodbrain barrier.
Rationale 5: Drugs used for emphysema would not cross the bloodbrain barrier.
Global Rationale: Drugs such as benzodiazepines, antipsychotic agents, antiseizure agents, and tranquilizers can cross the bloodbrain barrier in higher concentrations, resulting in adverse effects. Antibiotics for pneumonia do not cross the bloodbrain barrier. Drugs used for emphysema would not cross the bloodbrain barrier.