A nurse is preparing to administer a drug to a patient. The nurse ...

[Caiter2013]

A nurse is preparing to administer a drug to a patient. The nurse understands that the route by which bioavailability would most likely be affected is
 
  a. oral.
  b. subcutaneous.
  c. intramuscular.
  d. intravenous.

Question 2

A nurse is providing education to the unit on adverse drug reactions to reduce the number of medication errors.
 
  After the teaching has been conducted, the nurse asks, Which factor is a primary determinant of the intensity of an allergic drug reaction? The participants' best response would be the
  a. dose of drug ingested.
  b. body surface area of the patient.
  c. patient's degree of compliance.
  d. degree of sensitization.

[Sarahjh]

Answer to Question 1

ANS: A
Oral drugs must undergo a first-pass effect, and those drugs are subject to the acid in the gut, which may affect bioavailability.
Subcutaneous, intramuscular, and intravenous medications are not subject to the first-pass effect or the acidity of the gut, therefore bioavailability is least likely to be affected by these routes.

Answer to Question 2

ANS: D
The intensity of an allergic reaction is determined primarily by the degree of sensitization of the immune system, not by drug dosage.
The intensity of an allergic reaction is largely independent of dosage. The dose of the drug is not necessarily related to whether the patient experiences an allergic reaction.
The body surface area is used to determine dose and is not a primary determinant of an allergic reaction.
The patient's degree of compliance is not relevant to the development of an allergic reaction.

[Caiter2013]

TY

[Sarahjh]

You're welcome