This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A nurse is assisting in drug trials that have reached the stage in which potential new indications ... (Read 156 times)

awywial

  • Hero Member
  • *****
  • Posts: 577
on: Jul 23, 2018
A nurse is assisting in drug trials that have reached the stage in which potential new indications for approved drugs are investigated. The nurse is aware that this phase is known as phase:
 
  a. I.
  b. II.
  c. III.
  d. IV.

Question 2

Clinical experimentation occurs in four stages. The determination of the human dosage range based on responses in healthy subjects is a goal of phase _____ of human clinical experimentation.
 
  a. I
  b. II
  c. III
  d. IV


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Ashley I

  • Sr. Member
  • ****
  • Posts: 344
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: D
Phase IV studies may examine potential new indications for approved drugs.

Answer to Question 2

ANS: A
Phase I trials are primarily designed to assess safety. The objectives of phase I are to determine the human dosage range based on response in healthy human subjects and to identify the pharmacokinetics (i.e., absorption, distribution, metabolism/biotransformation, excretion/elimination) of the drug. Progression to the next phase occurs if no serious adverse effects are demonstrated, the drug is eliminated in a reasonable amount of time, and the dose range is below that known to induce pathology in animals.


awywial

  • Hero Member
  • *****
  • Posts: 577
Reply #2 on: Jul 23, 2018
Thanks


Ashley I

  • Sr. Member
  • ****
  • Posts: 344
Reply #3 on: Jul 23, 2018
Welcome :)


« previous next »
 

Did you know?

Approximately one in four people diagnosed with diabetes will develop foot problems. Of these, about one-third will require lower extremity amputation.

Did you know?

Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.

Did you know?

Carbamazepine can interfere with the results of home pregnancy tests. If you are taking carbamazepine, do not try to test for pregnancy at home.

Did you know?

A serious new warning has been established for pregnant women against taking ACE inhibitors during pregnancy. In the study, the risk of major birth defects in children whose mothers took ACE inhibitors during the first trimester was nearly three times higher than in children whose mothers didn't take ACE inhibitors. Physicians can prescribe alternative medications for pregnant women who have symptoms of high blood pressure.

Did you know?

Drugs are in development that may cure asthma and hay fever once and for all. They target leukotrienes, which are known to cause tightening of the air passages in the lungs and increase mucus productions in nasal passages.

Nurse examining and measuring hematuria sample from client with a UTI Nurse examining and measuring hematuria sample from client with a UTI
3.6 Vaginal drug administration: (a) instilling a vaginal suppository 3.6 Vaginal drug administration: (a) instilling a vaginal suppository
Documented Herb–Drug Interactions Documented Herb–Drug Interactions
Documented Herb–Drug Interactions Documented Herb–Drug Interactions
Clinically Significant Drug-Disease Interactions in Dentistry Clinically Significant Drug-Disease Interactions in Dentistry
Drug Label for Amlodipine Besylate Drug Label for Amlodipine Besylate
Video: baroreceptors

For a complete list of videos, visit our video library