This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A nurse is assisting in drug trials that have reached the stage in which potential new indications ... (Read 93 times)

awywial

  • Hero Member
  • *****
  • Posts: 577
on: Jul 23, 2018
A nurse is assisting in drug trials that have reached the stage in which potential new indications for approved drugs are investigated. The nurse is aware that this phase is known as phase:
 
  a. I.
  b. II.
  c. III.
  d. IV.

Question 2

Clinical experimentation occurs in four stages. The determination of the human dosage range based on responses in healthy subjects is a goal of phase _____ of human clinical experimentation.
 
  a. I
  b. II
  c. III
  d. IV


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

Ashley I

  • Sr. Member
  • ****
  • Posts: 344
Reply #1 on: Jul 23, 2018
Answer to Question 1

ANS: D
Phase IV studies may examine potential new indications for approved drugs.

Answer to Question 2

ANS: A
Phase I trials are primarily designed to assess safety. The objectives of phase I are to determine the human dosage range based on response in healthy human subjects and to identify the pharmacokinetics (i.e., absorption, distribution, metabolism/biotransformation, excretion/elimination) of the drug. Progression to the next phase occurs if no serious adverse effects are demonstrated, the drug is eliminated in a reasonable amount of time, and the dose range is below that known to induce pathology in animals.


awywial

  • Hero Member
  • *****
  • Posts: 577
Reply #2 on: Jul 23, 2018
Thanks


Ashley I

  • Sr. Member
  • ****
  • Posts: 344
Reply #3 on: Jul 23, 2018
Welcome :)


« previous next »
 

Did you know?

People with high total cholesterol have about two times the risk for heart disease as people with ideal levels.

Did you know?

Astigmatism is the most common vision problem. It may accompany nearsightedness or farsightedness. It is usually caused by an irregularly shaped cornea, but sometimes it is the result of an irregularly shaped lens. Either type can be corrected by eyeglasses, contact lenses, or refractive surgery.

Did you know?

The highest suicide rate in the United States is among people ages 65 years and older. Almost 15% of people in this age group commit suicide every year.

Did you know?

As the western states of America were settled, pioneers often had to drink rancid water from ponds and other sources. This often resulted in chronic diarrhea, causing many cases of dehydration and death that could have been avoided if clean water had been available.

Did you know?

When taking monoamine oxidase inhibitors, people should avoid a variety of foods, which include alcoholic beverages, bean curd, broad (fava) bean pods, cheese, fish, ginseng, protein extracts, meat, sauerkraut, shrimp paste, soups, and yeast.

A nurse prepares a client for anesthesia and surgery. A nurse prepares a client for anesthesia and surgery.
drug effects at synapses drug effects at synapses
Effect of stimulus strength on size of graded potential. Effect of stimulus strength on size of graded potential.
Summary of Drug Action: Common Routes of Administration Summary of Drug Action: Common Routes of Administration
Dose-response relationship. As the dose of a drug increases, a maximal response or plateau is ... Dose-response relationship. As the dose of a drug increases, a maximal response or plateau is ...
Drug Action Through Channels, via Voltage Changes or Chemicals Drug Action Through Channels, via Voltage Changes or Chemicals
Video: Prone Position

For a complete list of videos, visit our video library