Author Question: Food is known to increase, decrease, or delay drug absorption. A client has a high serum cholesterol ... (Read 39 times)

tiara099 · **on:** Jul 23, 2018

Food is known to increase, decrease, or delay drug absorption. A client has a high serum cholesterol level, and lovastatin (Mevacor) is prescribed. The client is taking the drug at mealtime and asks why this is necessary.

What does taking lovastatin with food accomplish?
a. Decrease in drug absorption
b. Decrease in drug absorption
c. Decrease in drug action
d. Increase in drug excretion

Question 2

Some drugs can affect the excretion of other drugs. The antidysrhythmic drug quinidine decreases the excretion of digoxin (Lanoxin). How would the digoxin concentration in the body fluids be affected?

a. No effect
b. Decreased
c. Increased
d. Unabsorbed

Anton · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

ANS: B
The absorption of the statin medications is increased in the presence of food.

Answer to Question 2

ANS: C
Because the excretion of digoxin (Lanoxin) is decreased, this would allow the digoxin to accumulate in the bloodstream.