A patient begins taking cholestyramine (Questran) to treat ...

[BRWH]

A patient begins taking cholestyramine (Questran) to treat hyperlipidemia. The patient reports abdominal discomfort and constipation. The nurse will provide which instruction to the patient?
 
  a. Increase fluid and slowly increase fiber intake.
  b. Stop taking the medication immediately.
  c. Take an over-the-counter laxative.
  d. Take the medication on an empty stomach.

Question 2

A patient has been taking cholestyramine (Questran) to treat hyperlipidemia type II. The patient reports abdominal cramping and constipation.
 
  The patient's serum low- density lipoprotein (LDL) has decreased from 170 mg/dL to 110 mg/dL, and triglycerides have not changed from 150 mg/dL since beginning the medication. The provider changes the medication to colesevelam HCl (Welchol).The patient asks the nurse why the medication was changed, and the nurse will explain that colesevelam HCl is ordered for which reason?
  a. It has fewer side effects.
  b. It has more convenient dosing.
  c. It provides greater LDL reduction.
  d. It provides greater triglyceride reduction.

[cpetit11]

Answer to Question 1

ANS: A
Cholestyramine can cause gastrointestinal upset and constipation, and these symptoms can be reduced with increased fluids and foods high in fiber. Stopping the medication is not indicated. Over-the-counter laxatives are not recommended until other methods have been tried. Giving the medication on an empty stomach will not relieve the discomfort.

Answer to Question 2

ANS: A
Colesevelam is similar to cholestyramine but has fewer gastrointestinal side effects. This patient has demonstrated good results with the bile acid sequestrant, so the provider needs to offer a preparation with fewer adverse effects. Both drugs are given twice daily.

[BRWH]

TYSM

[helenmarkerine]

Thanks for the timely response, appreciate it