Author Question: The nurse would correctly identify the major dose-limiting toxicity of cyclophosphamide (Cytoxan) as ... (Read 38 times)

CBme · **on:** Jul 23, 2018

The nurse would correctly identify the major dose-limiting toxicity of cyclophosphamide (Cytoxan) as

a. cystitis.
b. bone marrow suppression.
c. stomatitis.
d. pulmonary fibrosis.

Question 2

A patient on long-term corticosteroids develops a sudden and severe lower back pain after bending to pick up a book. The nurse should assess the patient for:

a. muscle spasm.
b. epidural bleeding.
c. compression fracture.
d. kidney stones.

mk6555 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

B
The major dose-limiting toxicity of cyclophosphamide is bone marrow suppression. Severe nau-sea, vomiting, and alopecia also are common, especially at high doses.
Cyclophosphamide can cause acute hemorrhagic cystitis, but this is not the major dose limiting effect.
Cyclophosphamide does not cause stomatitis or pulmonary fibrosis.

Answer to Question 2

c