This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient who is taking ketoconazole tells the nurse that her periods have become irregular. What ... (Read 90 times)

Destiiny22

  • Hero Member
  • *****
  • Posts: 557
on: Jul 23, 2018
A patient who is taking ketoconazole tells the nurse that her periods have become irregular. What will the nurse tell her?
 
  a. This indicates that she should begin taking oral contraceptives.
  b. This is caused by a reversible effect on estradiol synthesis.
  c. This is a serious side effect that warrants discontinuation of the drug.
  d. This is a sign of hepatic toxicity, and the drug dose should be lowered.

Question 2

A provider has ordered oral voriconazole Vfend for a patient who has a systemic fungal infection. The nurse obtains a medication history and learns that the patient takes phenobarbital for seizures.
 
  The nurse will contact the provider to discuss which possibility? a. Administering intravenous voriconazole
  b. Reducing the dose of phenobarbital
  c. Reducing the dose of voriconazole
  d. Using a different antifungal agent


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

olderstudent

  • Sr. Member
  • ****
  • Posts: 339
Reply #1 on: Jul 23, 2018
Answer to Question 1

B
Ketoconazole inhibits steroid synthesis in humans, and in females it reduces estradiol synthesis, causing menstrual irregularities. It is not an indication that oral contraceptive pills (OCPs) are needed. Because it is reversible, there is no indication for withdrawing the drug until treatment is complete. Menstrual irregularities are not a sign associated with hepatotoxicity.

Answer to Question 2

D
Voriconazole can interact with many drugs. It should not be combined with drugs that are po-werful P450 inhibitors, including phenobarbital, because these can reduce the levels of vorico-nazole. Administering the voriconazole IV will not increase the serum level. It is not correct to reduce the dose of either drug.


Destiiny22

  • Hero Member
  • *****
  • Posts: 557
Reply #2 on: Jul 23, 2018
Thanks


olderstudent

  • Sr. Member
  • ****
  • Posts: 339
Reply #3 on: Jul 23, 2018
Welcome :)


« previous next »
 

Did you know?

In 1885, the Lloyd Manufacturing Company of Albany, New York, promoted and sold "Cocaine Toothache Drops" at 15 cents per bottle! In 1914, the Harrison Narcotic Act brought the sale and distribution of this drug under federal control.

Did you know?

Studies show that systolic blood pressure can be significantly lowered by taking statins. In fact, the higher the patient's baseline blood pressure, the greater the effect of statins on his or her blood pressure.

Did you know?

The term bacteria was devised in the 19th century by German biologist Ferdinand Cohn. He based it on the Greek word "bakterion" meaning a small rod or staff. Cohn is considered to be the father of modern bacteriology.

Did you know?

A headache when you wake up in the morning is indicative of sinusitis. Other symptoms of sinusitis can include fever, weakness, tiredness, a cough that may be more severe at night, and a runny nose or nasal congestion.

Did you know?

Warfarin was developed as a consequence of the study of a strange bleeding disorder that suddenly occurred in cattle on the northern prairies of the United States in the early 1900s.

Taking a Patient’s Temperature with a Tympanic Thermometer Taking a Patient’s Temperature with a Tympanic Thermometer
The medical assistant is measuring the urine output from a patient who has an indwelling Foley ... The medical assistant is measuring the urine output from a patient who has an indwelling Foley ...
Areas of sclerosis (see arrows) in the white matter of a patient with MS. Areas of sclerosis (see arrows) in the white matter of a patient with MS.
The nurse begins the general survey The nurse begins the general survey
Video: Passive Smoke Exposure

For a complete list of videos, visit our video library