This topic contains a solution. Click here to go to the answer
« previous next »

Author Question: A patient who is taking ketoconazole tells the nurse that her periods have become irregular. What ... (Read 15 times)

Destiiny22

  • Hero Member
  • *****
  • Posts: 557
on: Jul 23, 2018
A patient who is taking ketoconazole tells the nurse that her periods have become irregular. What will the nurse tell her?
 
  a. This indicates that she should begin taking oral contraceptives.
  b. This is caused by a reversible effect on estradiol synthesis.
  c. This is a serious side effect that warrants discontinuation of the drug.
  d. This is a sign of hepatic toxicity, and the drug dose should be lowered.

Question 2

A provider has ordered oral voriconazole Vfend for a patient who has a systemic fungal infection. The nurse obtains a medication history and learns that the patient takes phenobarbital for seizures.
 
  The nurse will contact the provider to discuss which possibility? a. Administering intravenous voriconazole
  b. Reducing the dose of phenobarbital
  c. Reducing the dose of voriconazole
  d. Using a different antifungal agent


Related Topics

Need homework help now?

Ask unlimited questions for free

Ask a Question
Marked as best answer by a Subject Expert

olderstudent

  • Sr. Member
  • ****
  • Posts: 339
Reply #1 on: Jul 23, 2018
Answer to Question 1

B
Ketoconazole inhibits steroid synthesis in humans, and in females it reduces estradiol synthesis, causing menstrual irregularities. It is not an indication that oral contraceptive pills (OCPs) are needed. Because it is reversible, there is no indication for withdrawing the drug until treatment is complete. Menstrual irregularities are not a sign associated with hepatotoxicity.

Answer to Question 2

D
Voriconazole can interact with many drugs. It should not be combined with drugs that are po-werful P450 inhibitors, including phenobarbital, because these can reduce the levels of vorico-nazole. Administering the voriconazole IV will not increase the serum level. It is not correct to reduce the dose of either drug.


Destiiny22

  • Hero Member
  • *****
  • Posts: 557
Reply #2 on: Jul 23, 2018
Thanks


olderstudent

  • Sr. Member
  • ****
  • Posts: 339
Reply #3 on: Jul 23, 2018
Welcome :)


« previous next »
 

Did you know?

To combat osteoporosis, changes in lifestyle and diet are recommended. At-risk patients should include 1,200 to 1,500 mg of calcium daily either via dietary means or with supplements.

Did you know?

There used to be a metric calendar, as well as metric clocks. The metric calendar, or "French Republican Calendar" divided the year into 12 months, but each month was divided into three 10-day weeks. Each day had 10 decimal hours. Each hour had 100 decimal minutes. Due to lack of popularity, the metric clocks and calendars were ended in 1795, three years after they had been first marketed.

Did you know?

Blastomycosis is often misdiagnosed, resulting in tragic outcomes. It is caused by a fungus living in moist soil, in wooded areas of the United States and Canada. If inhaled, the fungus can cause mild breathing problems that may worsen and cause serious illness and even death.

Did you know?

Only one in 10 cancer deaths is caused by the primary tumor. The vast majority of cancer mortality is caused by cells breaking away from the main tumor and metastasizing to other parts of the body, such as the brain, bones, or liver.

Did you know?

Malaria mortality rates are falling. Increased malaria prevention and control measures have greatly improved these rates. Since 2000, malaria mortality rates have fallen globally by 60% among all age groups, and by 65% among children under age 5.

Critical thinking involves analysis in which the nurse examines patient data available from a variet Critical thinking involves analysis in which the nurse examines patient data available from a variet
An emergency medical technician positions defibrillator paddles on the chest of a supine male patien An emergency medical technician positions defibrillator paddles on the chest of a supine male patien
Lung cancer. Photograph of part of a lung removed after death. The yellow area is a large tumor and Lung cancer. Photograph of part of a lung removed after death. The yellow area is a large tumor and
Example of a patient’s ledger in practice management software. Example of a patient’s ledger in practice management software.
Aquamatic pad and heating unit provide dry heat treatment to a patient’s arm. Aquamatic pad and heating unit provide dry heat treatment to a patient’s arm.
How to calculate monthly payments at varying amortization periods (Question 2) How to calculate monthly payments at varying amortization periods (Question 2)
Video: Gastrin (gastric emptying) & Secretin (buffering gastric acid)

For a complete list of videos, visit our video library