Author Question: A nursing student asks the nurse why the provider has ordered a combination product containing an ... (Read 28 times)

Themember4 · **on:** Jul 23, 2018

A nursing student asks the nurse why the provider has ordered a combination product containing an opioid analgesic and an NSAID for a patient who has cancer. Which response by the nurse is correct?

a. There are decreased effects of NSAIDs on the GI tract when a combination prod-uct is used.
b. There are fewer adverse effects from both drugs when used in a combination product.
c. There is a decreased likelihood of opioid dependence when it is given in combina-tion with an NSAID.
d. There is increased pain relief with the combination than when either product is used alone.

Question 2

A nurse is discussing the differences between OxyContin OC and OxyContin OP with a group of nursing students. Which statement by a student indicates understanding of the teaching?

a. OxyContin OC cannot be drawn into a syringe for injection.
b. OxyContin OP has greater solubility in water and alcohol.
c. OxyContin OP is not easily crushed into a powder.
d. Patients using OxyContin OP are less likely to overdose.

anyusername12131 · **Reply #1 on:** Jul 23, 2018

Answer to Question 1

D
Because the two types of drugs work by different mechanisms, use of a combination product yields greater pain relief than either agent alone. The combination does not decrease the inci-dence of GI effects from NSAIDs or the incidence of other adverse effects from either drug and does not decrease the likelihood of opioid dependence.

Answer to Question 2

C
OxyContin OP is a newer formulation that is designed to reduce OxyContin abuse. The OP for-mulation is much harder to crush into a powder. The OC preparation can be crushed and dis-solved in water or alcohol and can easily be drawn into a syringe. The OP preparation does not dissolve easily in these solutions. Despite the differences in preparation, there is no indication that either form is less subject to abuse or overdose.