Answer to Question 1
C
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In patients treated with Epogen or any drug in this class who develop severe anemia after improvement, the drug should be stopped and should not be changed to another drug in the class because it is likely due to patient's development of neutralizing antibodies. Increasing the dosage will not help and changing the route of administration will not reverse the process after antibodies have formed.
Answer to Question 2
A
Feedback:
Cidofovir, which is given by IV infusion, reaches peak levels at the end of the infusion; in studies, it was cleared from the system within 15 minutes after the infusion was completed. It is excreted unchanged in the urine and must be given with probenecid to increase renal clearance of the drug. Paroxetine hydrochloride is Paxil, an antidepressant; Penciclovir is an antiviral cream; Prostigmin is an anticholinesterase agent used in myasthenia gravis. None of these drugs are used with cidofovir except for probenecid.
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