Which of these patients would the nurse expect to be the best ...

[jrubin]

Which of these patients would the nurse expect to be the best candidate for misoprostol (Cytotec)?
 
  A) A 12-year-old with obsessive-compulsive disorder
  B) A 22-year-old pregnant patient
  C) A 46-year-old trial lawyer with hypertension
  D) An 83-year-old man with rheumatoid arthritis

Question 2

The pathophysiology class is learning how microorganisms develop resistance to anti-infective drugs. What is one way the nursing students would learn that microorganisms develop resistance to anti-infective drugs?
 
  A) By rearranging their deoxyribonucleic acid (DNA) to produce membranes that are permeable to the drug
  B) By producing an enzyme that stimulates the drug
  C) By changing the cellular membrane to allow the drug entry into the cell
  D) By altering binding sites on the membrane or ribosomes so that the drug cannot enter the cell

[kkenney]

Answer to Question 1

D
Feedback:
The 83-year-old man with rheumatoid arthritis is most likely to be taking nonsteroidal anti-inflammatory drugs (NSAIDs). Misoprostol is indicated for prevention of NSAID induced ulcers in adults at high risk for development of gastric ulcers. The other three patients would not be candidates for this drug.

Answer to Question 2

D
Feedback:
Microorganisms have developed resistance by changing cellular permeability to prevent the drug from entering the cell by altering binding sites on the membranes or on ribosomes so the drug can no longer be accepted and by producing enzymes that deactivate the drug. Microorganisms have not been found to be able to rearrange their DNA to change their membrane structure.

[jrubin]

Thanks

[kkenney]

Welcome