Answer to Question 1
A
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Apple juice would be the best choice. Quinidine requires a slightly acidic urine (normal state) for excretion. Patients receiving quinidine should avoid foods that alkalinize the urine (e.g., citrus juices, vegetables, antacids, milk products), which could lead to increased quinidine levels and toxicity. Grapefruit juice has been shown to interfere with the metabolism of quinidine, leading to increased serum levels and toxic effects; this combination should be avoided.
Answer to Question 2
A
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Begin by converting the infant's weight to kilograms (12 pounds 2.2 pounds/kg = 5.45 kg). The order says to give 15 mg/kg. To determine this child's dosage multiply weight and 15 mg/kg (5.45 kg 15 mg/kg = 81.75 mg/dose). Finally, use the ratio and proportion method to calculate how to prepare the medication: 160 mg/5 mL = 81.75 mg/X mL; cross-multiplying yields 2.5 mL.