Answer to Question 1
A
Feedback:
The hydantoins stabilize nerve membranes throughout the central nervous system directly by influencing ionic channels in the cell membrane, thereby decreasing excitability and hyperexcitability to stimulation. By decreasing conduction through nerve pathways, they reduce the tonicclonic, muscular, and emotional responses to stimulation. Valproic acid and benzodiazepines increase gamma-aminobutyric acid (GABA) effects and decrease electrical activity. Carbamazepine increases GABA activity and blocks sodium and calcium channels to stop action potentials.
Answer to Question 2
A
Feedback:
Adjunctive therapy to treat peptic ulcer, overactive gastrointestinal (GI) disorders; neurogenic bladder or cystitis; parkinsonism; biliary or renal colic; to decrease secretions pre-operatively; treatment of partial heart block associated with vagal activity; treatment of rhinitis or anticholinesterase poisoning.