Answer to Question 1
D
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Flucytosine does not have proven safety and efficacy in children, and extreme caution should be exercised if it is ordered. Fluconazole, terbinafine, and griseofulvin have established pediatric doses and would be drugs of choice if appropriate for a particular infection.
Answer to Question 2
D
Feedback:
Venlafaxine mildly blocks reuptake of norepinephrine, 5-hydroxytriptamine, and dopamine. It has fewer adverse central nervous system effects than trazodone. Its popularity has increased with the introduction of an extended-release form that does away with the multiple daily doses that are required with the regular form. Venlafaxine is readily absorbed from the gastrointestinal (GI) tract, extensively metabolized in the liver, and excreted in urine. Adequate studies have not been done in pregnancy and lactation, so that it should be used during those times only if the benefit to the mother clearly outweighs the potential risk to the neonate. It is taken orally, which is the case with most antidepressants.
Buccal drug administration
The Three Names Given to a Drug
Potency and efficacy: (a) Drug A has a higher potency than drug B. (b) Drug A has a higher efficacy ...
Selected Drug–Food and Drug–Herbal Interactions
Movement of a drug through the body (pharmacokinetics): absorption, distribution, metabolism, and ...
The nurse begins the general survey