By what route would the nurse administer amphotericin B? A) ...

[jwb375]

By what route would the nurse administer amphotericin B?
 
  A) Intravenously
  B) Intramuscularly
  C) Orally
  D) Topically

Question 2

The nurse, assisting with Phase I drug studies, is talking with a woman who asks, Why can't I participate in this study? What would be the nurse's best response?
 
  A) Drugs pose a greater risk to women of reproductive age.
  B) Drugs are only tested on men because they are stronger.
  C) Women are more prone to adverse effects from medications.
  D) Drugs affect women differently than they affect women.

[macmac]

Answer to Question 1

A
Feedback:
Amphotericin B is only administered by the IV route. It cannot be given intramuscularly, orally, or topically.

Answer to Question 2

A
Feedback:
Phase I drug trials usually involve healthy male volunteers because chemicals may exert an unknown and harmful effect on ova in women which could result in fetal damage when the woman becomes pregnant. Drugs are tested on both men and women, but women must be fully informed of risks and sign a consent stating they understand the potential for birth defects. Women are not more prone to adverse effects of medications. Although some drugs may affect women differently than men, this is a rationale for why drugs need to be tested on women, not an explanation of why women are not included in a phase I study.

[jwb375]

Thanks

[macmac]

Welcome