A 17-year-old male patient with athlete's foot is extremely upset ...

[Shelles]

A 17-year-old male patient with athlete's foot is extremely upset that he cannot get rid of it. He calls the clinic and asks the nurse whether the doctor can give him an antibiotic to cure the infection.
 
   What should the nurse include in the explanation of treatment for fungal infections? A) Fungi differ from bacteria in that the fungus has flexible cell walls that allow for free transfer into and out of the cell.
  B) Protective layers contain sterols, which change the membrane permeability.
  C) The composition of the protective layers of the fungal cell makes the organism resistant to antibiotics.
  D) Fungi cell walls contain Candida, which makes the cells rigid.

Question 2

What concept is considered when generic drugs are substituted for brand name drugs?
 
  A) Bioavailability
  B) Critical concentration
  C) Distribution
  D) Half-life

[vkodali]

Answer to Question 1

C
Feedback:
The nurse should tell the patient that the composition of the protective layers of the fungal cell makes the organism resistant to antibiotics so that antibiotics would not have any positive effect. Fungi do differ from bacteria, but the fungus has rigid cell walls that allow for free transfer in and out of the cell. The protective layers contain ergosterol, not Candida, that helps keep the cell wall rigid, not permeable.

Answer to Question 2

A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available to act on body cells. Binders used in a generic drug may not be the same as those used in the brand name drug. Therefore, the way the body breaks down and uses the drug may differ, which may eliminate a generic drug substitution. Critical concentration is the amount of a drug that is needed to cause a therapeutic effect and should not differ between generic and brand name medications. Distribution is the phase of pharmacokinetics, which involves the movement of a drug to the body's tissues and is the same in generic and brand name drugs. A drug's half-life is the time it takes for the amount of drug to decrease to half the peak level, which should not change when substituting a generic medication.

[Shelles]

TY

[vkodali]

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