A patient with a complex medical history is considering the use ...

[Bob-Dole]

A patient with a complex medical history is considering the use of oral contraceptives. The nurse should be aware that many antibiotics and antiseizure medications cause what effect when combined with oral contraceptives?
 
  A) Increased risk of pregnancy
  B) Increased blood pressure
  C) Increased risk of thromboembolism
  D) Increased gastric acid

Question 2

A neonate has been prescribed a water-soluble drug for the treatment of an acute infection. The nurse recognizes that the percentage of body water in an infant is significantly higher than that of an adult.
 
  What implication does this have for pharmacotherapy of an infant? A) The drug will need to be emulsified before administration.
  B) The infant's fluid intake will be reduced before and after administration.
  C) The infant will have a fat-soluble drug substituted.
  D) The infant may require an increased dose of the drug.

[Leostella20]

Answer to Question 1

A
Feedback:
Several medications may reduce the effectiveness of oral contraceptives (i.e., increase the likelihood of pregnancy). These include several antibiotics and antiseizure medications. This combination does not increase blood pressure, risk of thromboembolism, or gastric acid secretion.

Answer to Question 2

D
Feedback:
In adults, total body water is approximately 60, whereas in newborns, it is 80. This difference means that water-soluble drugs are diluted easily and readily moved into intercellular tissue. As a result, serum drug concentrations are lower, and increased dosages of water-soluble drugs may be necessary to maintain therapeutic drug levels. Substitutes may not be available, and fluid restriction does not compensate for this physiological difference.

[Bob-Dole]

Both answers were spot on, thank you once again

[Leostella20]

Great! Please up vote