Author Question: On what is the selection of an antimicrobial agent based? a. Sensitivity of the microorganism to ... (Read 68 times)

Pineappleeh · **on:** Jul 24, 2018

On what is the selection of an antimicrobial agent based?

a. Sensitivity of the microorganism to the drug
b. Half-life of the medication
c. Therapeutic levels of the drug
d. Bioavailability of the drug

Question 2

An older adult who has septicemia is receiving IV aminoglycoside therapy. Which symptom is most important for the nurse to monitor?

a. Bone marrow suppression
b. Ototoxicity
c. Gastrointestinal (GI) distress
d. Photosensitivity

whitcassie · **Reply #1 on:** Jul 24, 2018

Answer to Question 1

ANS: A
The selection of the antimicrobial agent must be based on the sensitivity of the pathogen and the possible toxicity to the patient. The half-life of the drug is not a concern with selection in comparison to sensitivity. Therapeutic levels of the drug are not criteria for selection. Bioavailability is a lesser concern than sensitivity.

Answer to Question 2

ANS: B
Eighth cranial nerve damage can result from aminoglycoside therapy. Patients should be monitored during therapy and after therapy has been discontinued for signs and symptoms of ototoxicity, including dizziness, tinnitus, and progressive hearing loss. Aminoglycosides do not produce bone marrow depression; this is characteristic of treatment with chloramphenicol. Aminoglycosides do not typically produce GI distress. Aminogylcosides do not produce photosensitivity; this is characteristic of treatment with glycylcyclines.