Isosorbide dinitrate is a long-acting nitrate given twice daily. ...

[jeatrice]

Isosorbide dinitrate is a long-acting nitrate given twice daily. The schedule for administration is 7 a.m. and 2 p.m. because:
 
  1. Long-acting forms have a higher risk for toxicity.
  2. Orthostatic hypotension is a common adverse effect.
  3. It must be taken with milk or food.
  4. Nitrate tolerance can develop.

Question 2

Beta blockers are especially helpful for patients with exertional angina who also have:
 
  1. Arrhythmias
  2. Hypothyroidism
  3. Hyperlipidemia
  4. Atherosclerosis

[iceage]

Answer to Question 1

4

Answer to Question 2

1

[jeatrice]

Thanks for the timely response, appreciate it

[bulacsom]

Excellent