Author Question: Isosorbide dinitrate is a long-acting nitrate given twice daily. The schedule for administration is ... (Read 24 times)

jeatrice · **on:** Jul 24, 2018

Isosorbide dinitrate is a long-acting nitrate given twice daily. The schedule for administration is 7 a.m. and 2 p.m. because:

1. Long-acting forms have a higher risk for toxicity.
2. Orthostatic hypotension is a common adverse effect.
3. It must be taken with milk or food.
4. Nitrate tolerance can develop.

Question 2

Beta blockers are especially helpful for patients with exertional angina who also have:

1. Arrhythmias
2. Hypothyroidism
3. Hyperlipidemia
4. Atherosclerosis