Author Question: Once they have been metabolized by the liver, the metabolites may be: 1. More active than the ... (Read 71 times)

Arii_bell · **on:** Jul 24, 2018

Once they have been metabolized by the liver, the metabolites may be:

1. More active than the parent drug
2. Less active than the parent drug
3. Totally deactivated so they are excreted without any effect
4. All of the above

Question 2

Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true?

1. Water soluble and ionized drugs cross these barriers rapidly.
2. The blood-brain barrier slows the entry of many drugs into and from brain cells.
3. The fetal-placental barrier protects the fetus from drugs taken by the mother.
4. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women.