Once they have been metabolized by the liver, the metabolites may ...

[Arii_bell]

Once they have been metabolized by the liver, the metabolites may be:
 
  1. More active than the parent drug
  2. Less active than the parent drug
  3. Totally deactivated so they are excreted without any effect
  4. All of the above

Question 2

Which of the following statements about the major distribution barriers (blood-brain or fetal-placental) is true?
 
  1. Water soluble and ionized drugs cross these barriers rapidly.
  2. The blood-brain barrier slows the entry of many drugs into and from brain cells.
  3. The fetal-placental barrier protects the fetus from drugs taken by the mother.
  4. Lipid-soluble drugs do not pass these barriers and are safe for pregnant women.

[alexanderhamilton]

Answer to Question 1

4

Answer to Question 2

2

[Arii_bell]

Thanks for the timely response, appreciate it

[yeungji]

Excellent