Drugs that have a significant first-pass effect: 1. Must be ...

[fagboi]

Drugs that have a significant first-pass effect:
 
  1. Must be given by the enteral (oral) route only
  2. Bypass the hepatic circulation
  3. Are rapidly metabolized by the liver and may have little if any desired action
  4. Are converted by the liver to more active and fat-soluble forms

Question 2

The route of excretion of a volatile drug will likely be the:
 
  1. Kidneys
  2. Lungs
  3. Bile and feces
  4. Skin

[dreamfighter72]

Answer to Question 1

3

Answer to Question 2

2

[fagboi]

Both answers were spot on, thank you once again

[dreamfighter72]

Great! Please up vote