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Of the estimated 2 million heroin users in the United States, 600,000–800,000 are considered hardcore addicts. Heroin addiction is considered to be one of the hardest addictions to recover from.
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Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.
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Long-term mental and physical effects from substance abuse include: paranoia, psychosis, immune deficiencies, and organ damage.
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More than nineteen million Americans carry the factor V gene that causes blood clots, pulmonary embolism, and heart disease.
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More than 2,500 barbiturates have been synthesized. At the height of their popularity, about 50 were marketed for human use.