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Signs of depression include feeling sad most of the time for 2 weeks or longer; loss of interest in things normally enjoyed; lack of energy; sleep and appetite disturbances; weight changes; feelings of hopelessness, helplessness, or worthlessness; an inability to make decisions; and thoughts of death and suicide.
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Thyroid conditions cause a higher risk of fibromyalgia and chronic fatigue syndrome.
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Lower drug doses for elderly patients should be used first, with titrations of the dose as tolerated to prevent unwanted drug-related pharmacodynamic effects.
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Medication errors are three times higher among children and infants than with adults.
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About 100 new prescription or over-the-counter drugs come into the U.S. market every year.