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The first oral chemotherapy drug for colon cancer was approved by FDA in 2001.
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There are major differences in the metabolism of morphine and the illegal drug heroin. Morphine mostly produces its CNS effects through m-receptors, and at k- and d-receptors. Heroin has a slight affinity for opiate receptors. Most of its actions are due to metabolism to active metabolites (6-acetylmorphine, morphine, and morphine-6-glucuronide).
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Approximately 15–25% of recognized pregnancies end in miscarriage. However, many miscarriages often occur before a woman even knows she is pregnant.
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Women are 50% to 75% more likely than men to experience an adverse drug reaction.
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Thyroid conditions may make getting pregnant impossible.