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Cocaine was isolated in 1860 and first used as a local anesthetic in 1884. Its first clinical use was by Sigmund Freud to wean a patient from morphine addiction. The fictional character Sherlock Holmes was supposed to be addicted to cocaine by injection.
After a vasectomy, it takes about 12 ejaculations to clear out sperm that were already beyond the blocked area.
The B-complex vitamins and vitamin C are not stored in the body and must be replaced each day.
The first monoclonal antibodies were made exclusively from mouse cells. Some are now fully human, which means they are likely to be safer and may be more effective than older monoclonal antibodies.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.