Phosphofructokinase is an allosteric enzyme that catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, an early step of glycolysis. In the presence of oxygen, an increase in the amount of ATP in a cell would be expected to
A) inhibit the enzyme and thus slow the rates of glycolysis and the citric acid cycle.
B) activate the enzyme and thus slow the rates of glycolysis and the citric acid cycle.
C) inhibit the enzyme and thus increase the rates of glycolysis and the citric acid cycle.
D) activate the enzyme and increase the rates of glycolysis and the citric acid cycle.
E) inhibit the enzyme and thus increase the rate of glycolysis and the concentration of citrate.
The steps of an enzyme-catalyzed reaction
Allosteric Effectors of Hemoglobin
Reaction coordinate diagram for a simple enzyme catalyzed reaction
Bypass 1: Conversion of Pyruvate to Phosphoenolpyruvate
Glutamate dehydrogenase catalyzes the reductive amination of a-ketoglutarate
Conversion factors derivation.