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Coca-Cola originally used coca leaves and caffeine from the African kola nut. It was advertised as a therapeutic agent and "pickerupper." Eventually, its formulation was changed, and the coca leaves were removed because of the effects of regulation on cocaine-related products.
Asthma cases in Americans are about 75% higher today than they were in 1980.
In inpatient settings, adverse drug events account for an estimated one in three of all hospital adverse events. They affect approximately 2 million hospital stays every year, and prolong hospital stays by between one and five days.
Most childhood vaccines are 90–99% effective in preventing disease. Side effects are rarely serious.
In 1844, Charles Goodyear obtained the first patent for a rubber condom.