Answer to Question 1
Alcohol crosses the placenta freely and is directly toxic.
A sudden dose of alcohol can halt the delivery of oxygen through the umbilical cord. The fetal brain and nervous system are extremely vulnerable to a glucose or oxygen deficit, and alcohol causes both by disrupting placental functioning.
Alcohol slows cell division, reducing the number of cells produced and inflicting abnormalities on those that are produced and all of their progeny.
During the first month of pregnancy, the fetal brain is growing at the rate of 100,000 new brain cells a minute. Even a few minutes of alcohol exposure during this critical period can exert a major detrimental effect.
Alcohol interferes with placental transport of nutrients to the fetus and can cause malnutrition in the mother; then all of malnutrition's harmful effects compound the effects of the alcohol.
Before fertilization, alcohol can damage the ovum or sperm in the mother- or father-to-be, leading to abnormalities in the child.
Answer to Question 2
The placenta is both a supply depot and a waste-removal system for the fetus. If the placenta works perfectly, the fetus wants for nothing; if it doesn't, no alternative source of sustenance is available, and the fetus will fail to thrive. If the mother's nutrient stores are inadequate during placental development, no amount of nutrients later on in pregnancy can make up for the lack. If the placenta fails to form or function properly, the fetus will not receive optimal nourishment. After getting such a poor start on life, the child may be ill equipped, even as an adult, to store sufficient nutrients, and a girl may later be unable to grow an adequate placenta or bear healthy full-term infants.