Describe the effect of obesity on the development of gestational ...

[shenderson6]

Describe the effect of obesity on the development of gestational and type 2 diabetes.

Question 2

Which of the following are acidic, water-soluble compounds formed from the incomplete breakdown of fat when carbohydrate is not available?
 
 a. amino acids
  b. pyruvate molecules
  c. carbon dioxide
  d. ketone bodies
  e. ammonia and urea

[mjbamaung]

Answer to Question 1

People with gestational diabetes or type 2 are generally obese and have insulin resistance. Insulin resistance that develops with obesity partly originates from metabolic changes initiated in fat cells. High amounts of body fat are related to an increased release of fatty acids from fat cells into blood. High circulating levels of fatty acids stimulate the production of free radicals and other proinflammatory molecules and the development of oxidative stress and chronic inflammation. These and other changes are related to the development of insulin resistance in liver and muscle cells, excessive fat storage in the liver, and increased insulin output by beta cells of the pancreas. Over time, insulin resistance can lead to the exhaustion of beta cells and decreased insulin production, elevated blood glucose levels, and the onset of type 2 diabetes

Answer to Question 2

d

[shenderson6]

Thanks for the timely response, appreciate it

[hollysheppard095]

Excellent