Answer to Question 1
Weight loss of greater than 10 of body weight; persistent constitutional symptoms such as fever, diarrhea; oral candidiasis (Candida albicans) or hairy leukoplakia; acute necrotizing ulcerative gingivitis or necrotizing ulcerative periodontitis within the oral cavity; pulmonary tuberculosis; severe bacterial infections in the lungs, GI tract; unexplained anemia, neutropenia, and/or thrombocytopenia for more than a month (confirmatory testing is required for anemias).
Answer to Question 2
angina