Answer to Question 1
The relationship between nutrition status and long-term survival of individuals with CF is well documented. Pancreatic insufficiency results in poor digestion, poor absorption of fat and fat-soluble vitamins, and loss of bile and bile salts. Chronic pulmonary infections and deteriorating pulmonary function may lead to anorexia, increased energy requirements, and malnutrition. The more malnourished the patient is, the poorer his or her lung function. Children with CF may have stunted growth and inadequate weight gain because of inadequate supplies of nutrients due to a combination of anorexia and poor nutrient absorption. Lower-than-average height and weight are particularly pronounced in infants, adolescents, and individuals newly diagnosed with CF.
Answer to Question 2
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